Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02XQX
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| Former ID |
DNC014823
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| Drug Name |
ETHIOFENCARB
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| Synonyms |
Ethiofencarb; 29973-13-5; CRONETON; Arylmate; Kronetone; Croneton 500; Ethiophencarbe; Ethiofencarb [BSI:ISO]; alpha-Ethylthio-o-tolyl methylcarbamate; Hox 1901; 2-((Ethylthio)methyl)phenol methylcarbamate; 2-((Ethylthio)methyl)phenyl methylcarbamate; BAY-HOX-1901; Caswell No. 263AA; CHOX 1901; alpha-(Ethylthio)-o-tolyl methylcarbamate; UNII-FY0YB813XV; Ethiophencarbe [ISO-French]; 2-Ethylthiomethylphenyl N-methylcarbamate; HSDB 7140; (2-Ethylthiomethyl-phenyl)-N-methylcarbamate; EINECS 249-981-9
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H15NO2S
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| Canonical SMILES |
CCSCC1=CC=CC=C1OC(=O)NC
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| InChI |
1S/C11H15NO2S/c1-3-15-8-9-6-4-5-7-10(9)14-11(13)12-2/h4-7H,3,8H2,1-2H3,(H,12,13)
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| InChIKey |
HEZNVIYQEUHLNI-UHFFFAOYSA-N
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| CAS Number |
CAS 29973-13-5
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:38483
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hormone sensitive lipase (LIPE) | Target Info | Inhibitor | [1] |
| BioCyc | Triacylglycerol degradation | |||
| KEGG Pathway | cAMP signaling pathway | |||
| AMPK signaling pathway | ||||
| Insulin signaling pathway | ||||
| Panther Pathway | Triacylglycerol metabolism | |||
| Reactome | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |||
| WikiPathways | Insulin Signaling | |||
| Triacylglyceride Synthesis | ||||
| Lipid digestion, mobilization, and transport | ||||
| Adipogenesis | ||||
| Fatty Acid Beta Oxidation | ||||
| AMPK Signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Combining ligand-based pharmacophore modeling, quantitative structure-activity relationship analysis and in silico screening for the discovery of n... J Med Chem. 2008 Oct 23;51(20):6478-94. | |||
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