Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02YHA
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| Former ID |
DNC002733
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| Drug Name |
Geranyl Diphosphate
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| Synonyms |
Geranyl diphosphate; geranyl pyrophosphate; 763-10-0; Neryl pyrophosphate; Polyprenyl diphosphate; CHEBI:17211; Polyisopentenyldiphosphate; Polyisopentenylpyrophosphate; trans-Geranyl pyrophosphate; trans-Polyisopentenyldiphosphate; geranyl-PP; all-trans-Polyprenyl diphosphate; GPP; GVVPGTZRZFNKDS-JXMROGBWSA-N; geranyl-diphosphate; (2E)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate; geranyl-pyrophosphate; trans-3,7-Dimethyl-2,6-octadienyl pyrophosphate; [(2E)-3,7-dimethylocta-2,6-dienyl] phosphono hydrogen phosphate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H20O7P2
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| Canonical SMILES |
CC(=CCCC(=CCOP(=O)(O)OP(=O)(O)O)C)C
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| InChI |
1S/C10H20O7P2/c1-9(2)5-4-6-10(3)7-8-16-19(14,15)17-18(11,12)13/h5,7H,4,6,8H2,1-3H3,(H,14,15)(H2,11,12,13)/b10-7+
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| InChIKey |
GVVPGTZRZFNKDS-JXMROGBWSA-N
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| CAS Number |
CAS 763-10-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3634, 8140, 584640, 585257, 3288096, 6436301, 6436583, 7887969, 10299809, 10317539, 14801110, 24895272, 26706419, 26711762, 26712600, 26744185, 36888539, 46504900, 50139708, 50350999, 57404712, 74382092, 85164380, 87246610, 96099808, 103220066, 104635514, 117365621, 126523936, 135076056, 135229103, 135651490, 137104590, 137117165, 160965734, 162221866, 163821547, 164810612, 172659355, 173332104, 175443539, 179292974, 191112586, 223733332, 226483135, 226483136, 241131794, 250133584
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| ChEBI ID |
CHEBI:17211
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Geranyltranstransferase (FDPS) | Target Info | Inhibitor | [2] |
| BioCyc | Superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) | |||
| Superpathway of cholesterol biosynthesis | ||||
| Trans, trans-farnesyl diphosphate biosynthesis | ||||
| Geranylgeranyldiphosphate biosynthesis | ||||
| KEGG Pathway | Terpenoid backbone biosynthesis | |||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| Influenza A | ||||
| HTLV-I infection | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Cholesterol biosynthesis | |||
| Pathwhiz Pathway | Steroid Biosynthesis | |||
| Reactome | Cholesterol biosynthesis | |||
| Activation of gene expression by SREBF (SREBP) | ||||
| WikiPathways | Activation of Gene Expression by SREBP (SREBF) | |||
| SREBP signalling | ||||
| Cholesterol Biosynthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3051). | |||
| REF 2 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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