Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03CWL
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| Former ID |
DNC010500
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| Drug Name |
Methyl 3-(1-Benzyl-1H-imidazol-5-yl)-propanoate
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| Synonyms |
CHEMBL608140; Methyl 3-(1-Benzyl-1H-imidazol-5-yl)-propanoate; SCHEMBL9642312; FEWHBUJYQHXFMV-UHFFFAOYSA-N; BDBM50307219; 1-benzyl-5-imidazole propionic acid methyl ester
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H16N2O2
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| Canonical SMILES |
COC(=O)CCC1=CN=CN1CC2=CC=CC=C2
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| InChI |
1S/C14H16N2O2/c1-18-14(17)8-7-13-9-15-11-16(13)10-12-5-3-2-4-6-12/h2-6,9,11H,7-8,10H2,1H3
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| InChIKey |
FEWHBUJYQHXFMV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. | |||
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