Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03DKR
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| Former ID |
DIB012428
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| Drug Name |
GALAMUSTINE HYDROCHLORIDE
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| Synonyms |
C6-GLM; C6-GalM; C6-Galactose mustard; G-6-M; Galamustine hydrochloride; 6-[Bis(2-chloroethyl)amino]-6-deoxy-D-galactopyranose hydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Phase 1 | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C10H20Cl3NO5
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| Canonical SMILES |
C(CCl)N(CCCl)CC1C(C(C(C(O1)O)O)O)O.Cl
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| InChI |
1S/C10H19Cl2NO5.ClH/c11-1-3-13(4-2-12)5-6-7(14)8(15)9(16)10(17)18-6;/h6-10,14-17H,1-5H2;1H/t6-,7+,8+,9-,10?;/m1./s1
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| InChIKey |
YPEQSOJVCFFDKJ-IBUKJIQJSA-N
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| CAS Number |
CAS 107811-63-2
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human Deoxyribonucleic acid (hDNA) | Target Info | Antagonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002476) | |||
| REF 2 | 6-[Bis(2-chloroethyl)amino]-6-deoxygalactopyranose hydrochloride (C6-galactose mustard), a new alkylating agent with reduced bone marrow toxicity. Cancer Res. 1987 Feb 1;47(3):696-9. | |||
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