Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03DNV
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| Former ID |
DIB018878
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| Drug Name |
ARI-3099
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| Synonyms |
compound 6 [PMID: 23594271]; compound 226 [PMID: 24997602]; Py(D)AlaboroPro
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C13H18BN3O4
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| Canonical SMILES |
B(C1CCCN1C(=O)C(C)NC(=O)C2=CC=NC=C2)(O)O
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| InChI |
1S/C13H18BN3O4/c1-9(16-12(18)10-4-6-15-7-5-10)13(19)17-8-2-3-11(17)14(20)21/h4-7,9,11,20-21H,2-3,8H2,1H3,(H,16,18)/t9-,11+/m1/s1
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| InChIKey |
DRBWRJPFNOBNIO-KOLCDFICSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Acylamino-acid-releasing enzyme (APEH) | Target Info | Inhibitor | [1] |
| Prolyl endopeptidase FAP (FAP) | Target Info | Inhibitor | [2] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. Nat Chem Biol. 2014 Aug;10(8):656-63. | |||
| REF 2 | Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase. J Med Chem. 2013 May 9;56(9):3467-77. | |||
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