Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03DTQ
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| Former ID |
DIB015543
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| Drug Name |
PMX-700
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| Synonyms |
SJ-005019; SJ-005059; DC-010-116; Temozolomide analogs (cancer), Pharminox
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| Indication | Glioblastoma multiforme [ICD-11: 2A00.0; ICD-9: 191] | Investigative | [1] | |
| Company |
Pharminox Ltd
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA [cytosine-5]-methyltransferase 1 (DNMT1) | Target Info | Modulator | [1] |
| KEGG Pathway | Cysteine and methionine metabolism | |||
| Metabolic pathways | ||||
| MicroRNAs in cancer | ||||
| Pathwhiz Pathway | Methionine Metabolism | |||
| Pathway Interaction Database | Regulation of retinoblastoma protein | |||
| Reactome | PRC2 methylates histones and DNA | |||
| NoRC negatively regulates rRNA expression | ||||
| DNA methylation | ||||
| WikiPathways | Trans-sulfuration and one carbon metabolism | |||
| Retinoblastoma (RB) in Cancer | ||||
| One Carbon Metabolism | ||||
| Trans-sulfuration pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2605). | |||
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