Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03EQH
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| Former ID |
DNC012269
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| Drug Name |
RIPAZEPAM
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| Synonyms |
RIPAZEPAM; Pyrazapon; 26308-28-1; CI-683; Ripazepam [USAN:INN]; Ripazepamum [INN-Latin]; CCRIS 552; UNII-92000WH9C9; Cl-683; BRN 0819726; CHEBI:82529; 92000WH9C9; 1-ethyl-3-methyl-8-phenyl-4,6-dihydropyrazolo[4,3-e][1,4]diazepin-5(1H)-one; 1-Ethyl-4,6-dihydro-3-methyl-8-phenylpyrazolo(4,3-e)(1,4)diazepin-5(1H)-one; 1-Ethyl-1,4,5,6-tetrahydro-3-methyl-8-phenylpyrazolo(4,3-e)(1,4)diazepin-5-on; C15H16N4O; Ripazepamum; Pyrazolo(4,3-e)(1,4)diazepin-5(1H)-one, 4,6-dihydro-1-ethyl-3-methyl-8-phenyl-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H16N4O
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| Canonical SMILES |
CCN1C2=C(C(=N1)C)NC(=O)CN=C2C3=CC=CC=C3
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| InChI |
1S/C15H16N4O/c1-3-19-15-13(10(2)18-19)17-12(20)9-16-14(15)11-7-5-4-6-8-11/h4-8H,3,9H2,1-2H3,(H,17,20)
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| InChIKey |
YFHYNLHGFKXAIQ-UHFFFAOYSA-N
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| CAS Number |
CAS 26308-28-1
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:82529
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and interaction of 5-(substituted-phenyl)-3-methyl-6,7-dihydropyrazolo[4,3-e] [1,4]diazepin-8(7H)-ones with benzodiazepine receptors in r... J Med Chem. 1985 May;28(5):683-5. | |||
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