Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03FEV
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| Former ID |
DNC006435
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| Drug Name |
N-methyl-2-(pyridin-3-yloxy)ethanamine
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| Synonyms |
CHEMBL112221; 228272-00-2; N-methyl-2-(pyridin-3-yloxy)ethanamine; SCHEMBL7101352; CTK0J6067; DTXSID50430732; HKLZABNBARUZMN-UHFFFAOYSA-N; Methyl(2-(3-pyridyloxy)ethyl)amine; BDBM50120586; Methyl 2-(3-pyridinyloxy)ethylamine; AKOS011738046; N-methyl-2-(pyridin-3-yloxy)ethanaminium; Methyl-[2-(pyridin-3-yloxy)-ethyl]-amine; Ethanamine, N-methyl-2-(3-pyridinyloxy)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H12N2O
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| Canonical SMILES |
CNCCOC1=CN=CC=C1
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| InChI |
1S/C8H12N2O/c1-9-5-6-11-8-3-2-4-10-7-8/h2-4,7,9H,5-6H2,1H3
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| InChIKey |
HKLZABNBARUZMN-UHFFFAOYSA-N
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| CAS Number |
CAS 228272-00-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuronal acetylcholine receptor alpha-4 (CHRNA4) | Target Info | Inhibitor | [1] |
| Neuronal acetylcholine receptor beta-2 (CHRNB2) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Cholinergic synapse | ||||
| Nicotine addiction | ||||
| Panther Pathway | Nicotinic acetylcholine receptor signaling pathway | |||
| Nicotine pharmacodynamics pathway | ||||
| Reactome | Highly sodium permeable acetylcholine nicotinic receptors | |||
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | ||||
| Highly calcium permeable nicotinic acetylcholine receptors | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Nicotine Activity on Dopaminergic Neurons | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and analgesic activity of secondary amine analogues of pyridylmethylamine and positional isomeric analogues of ABT-594. Bioorg Med Chem Lett. 2006 Apr 1;16(7):2013-6. | |||
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