Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03HDP
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| Former ID |
DIB001065
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| Drug Name |
ACEA-1416
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| Synonyms |
Glystatin series member (1416), CoCensys
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| Indication | Cerebrovascular ischaemia [ICD-11: 8B1Z; ICD-10: I67.8; ICD-9: 434.91] | Terminated | [1] | |
| Company |
Purdue Neuroscience Corp
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| Structure |
 |
Download2D MOL |
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| Formula |
C9H6ClN3O4
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| Canonical SMILES |
CC1=C(C=C2C(=C1[N+](=O)[O-])NC(=O)C(=O)N2)Cl
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| InChI |
1S/C9H6ClN3O4/c1-3-4(10)2-5-6(7(3)13(16)17)12-9(15)8(14)11-5/h2H,1H3,(H,11,14)(H,12,15)
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| InChIKey |
CODLITRXBIRDTG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007961) | |||
| REF 2 | Tolerance develops to the antinociceptive and motor impairing effects of ACEA-1416, a NMDA receptor antagonist, in the formalin and rotarod test in mice. Pharmacol Res. 1998 Apr;37(4):295-302. | |||
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