Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03JTL
|
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| Drug Name |
APVO414
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| Synonyms |
MOR209/ES414
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| Indication | Prostate cancer [ICD-11: 2C82.0] | Phase 1 | [1] | |
| Company |
Aptevo Therapeutics Seattle, WAMorphoSysPlanegg, Germany
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate carboxypeptidase II (GCPII) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Metabolic pathways | ||||
| Vitamin digestion and absorption | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Reactome | Amino acid synthesis and interconversion (transamination) | |||
| WikiPathways | One Carbon Metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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