Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03NBX
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| Former ID |
DNC009459
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| Drug Name |
P-hydroxyphenethyl trans-ferulate
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| Synonyms |
p-Hydroxyphenethyl trans-ferulate; 84873-15-4; CHEMBL481245; Hydroxyphenethylferulate; AC1LCTXZ; SCHEMBL12298709; 4-Hydroxyphenethyl trans-ferulate; DTXSID10348425; MolPort-039-063-541; BCP16493; ZINC14503833; BDBM50259746; 9566AF; (4-Hydroxyphenyl)ethyl trans-ferulate; AKOS025288299; 3-(3-Methoxy-4-hydroxyphenyl)acrylic acid 4-hydroxyphenethyl ester; 2-(4-hydroxyphenyl)ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate; 2-(4-hydroxyphenyl)ethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H18O5
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| Canonical SMILES |
COC1=C(C=CC(=C1)C=CC(=O)OCCC2=CC=C(C=C2)O)O
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| InChI |
1S/C18H18O5/c1-22-17-12-14(4-8-16(17)20)5-9-18(21)23-11-10-13-2-6-15(19)7-3-13/h2-9,12,19-20H,10-11H2,1H3/b9-5+
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| InChIKey |
JMSFLLZUCIXALN-WEVVVXLNSA-N
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| CAS Number |
CAS 84873-15-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 7 receptor (HTR7) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Ras signaling pathway | |||
| Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Pathwhiz Pathway | Excitatory Neural Signalling Through 5-HTR 7 and Serotonin | |||
| Reactome | Serotonin receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis. J Nat Prod. 2006 Apr;69(4):536-41. | |||
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