Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03NTD
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| Former ID |
DNC006904
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| Drug Name |
3,4',5-trimethoxy-(Z)-stilbene
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| Synonyms |
(Z)-3,5,4'-TRIMETHOXYSTILBENE; cis-trismethoxy Resveratrol; 94608-23-8; CHEMBL311636; (Z)-3,4',5-trimethoxystilbene; cis-Trismethoxyresveratrol; cis-Stilbene Derivative, 5a; SCHEMBL1006207; ZINC9252; 8Z-3,4',5-trimethoxystilbene; BDBM23940; MolPort-009-018-268; GDHNBPHYVRHYCC-PLNGDYQASA-N; (Z)-3,5,40-Trimethoxystilbene; HMS3648G16; 1101AH; AKOS025401671; AC-24237; DB-079973; 608T238; SR-01000946368; SR-01000946368-1; I14-7426; 1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]benzene
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C17H18O3
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| Canonical SMILES |
COC1=CC=C(C=C1)C=CC2=CC(=CC(=C2)OC)OC
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| InChI |
1S/C17H18O3/c1-18-15-8-6-13(7-9-15)4-5-14-10-16(19-2)12-17(11-14)20-3/h4-12H,1-3H3/b5-4-
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| InChIKey |
GDHNBPHYVRHYCC-PLNGDYQASA-N
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| CAS Number |
CAS 94608-23-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tubulin beta (TUBB) | Target Info | Inhibitor | [1] |
| Tubulin beta-2 chain (TUBB2) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Phagosome | |||
| Gap junction | ||||
| Pathogenic Escherichia coli infection | ||||
| NetPath Pathway | FSH Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| EGFR1 Signaling Pathway | ||||
| Panther Pathway | Cytoskeletal regulation by Rho GTPase | |||
| Huntington disease | ||||
| Reactome | Regulation of PLK1 Activity at G2/M Transition | |||
| Loss of Nlp from mitotic centrosomes | ||||
| Recruitment of mitotic centrosome proteins and complexes | ||||
| Loss of proteins required for interphase microtubule organization?from the centrosome | ||||
| Anchoring of the basal body to the plasma membrane | ||||
| WikiPathways | Parkin-Ubiquitin Proteasomal System pathway | |||
| Pathogenic Escherichia coli infection | ||||
| Mitotic G2-G2/M phases | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents. J Med Chem. 2006 Oct 19;49(21):6412-5. | |||
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