Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03NWH
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| Former ID |
DNC011771
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| Drug Name |
2-(3-Bromo-phenyl)-chromen-4-one
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| Synonyms |
3'-Bromoflavone; CHEMBL55148; 2-(3-bromophenyl)chromen-4-one; 2-(3-Bromo-phenyl)-chromen-4-one; AC1LAQPY; SCHEMBL6654321; MolPort-001-904-025; ZINC265291; AKOS000603552; BAS 01121885; 4H-1-Benzopyran-4-one, 2-(3-bromophenyl)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H9BrO2
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=O)C=C(O2)C3=CC(=CC=C3)Br
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| InChI |
1S/C15H9BrO2/c16-11-5-3-4-10(8-11)15-9-13(17)12-6-1-2-7-14(12)18-15/h1-9H
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| InChIKey |
YFEZLTPSCJWVHI-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of halogenated/nitrated flavone derivatives and evaluation of their affinity for the central benzodiazepine receptor, Bioorg. Med. Chem. Lett. 7(15):2003-2008 (1997). | |||
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