Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03NZM
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| Former ID |
DIB001599
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| Drug Name |
T-588
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| Synonyms |
(-)-(R)-1-(Benzothiophen-5-yl)-2-[2-(diethylamino)ethoxy]ethanol hydrochloride; 131965-06-5
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| Drug Type |
Small molecular drug
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| Indication | Amyotrophic lateral sclerosis [ICD-11: 8B60.0; ICD-9: 335.2] | Discontinued in Phase 2 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H24ClNO2S
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| Canonical SMILES |
CCN(CC)CCOCC(C1=CC2=C(C=C1)SC=C2)O.Cl
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| InChI |
1S/C16H23NO2S.ClH/c1-3-17(4-2)8-9-19-12-15(18)13-5-6-16-14(11-13)7-10-20-16;/h5-7,10-11,15,18H,3-4,8-9,12H2,1-2H3;1H/t15-;/m0./s1
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| InChIKey |
BKMCUGFGPQNYHG-RSAXXLAASA-N
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| CAS Number |
CAS 142935-03-3
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Vesicular acetylcholine transporter (SLC18A3) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002000) | |||
| REF 2 | Involvement of noradrenaline transporters in S-nitrosocysteine-stimulated noradrenaline release from rat brain slices: existence of functional Na(+)-independent transporter activity. Neurochem Int. 2001 Apr;38(4):323-31. | |||
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