Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03OQK
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| Former ID |
DNC013033
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| Drug Name |
NSC-380292
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| Synonyms |
NSC-380292; CHEMBL206629; 89110-18-9; NSC380292; Benzo(b)cyclobuta(d)thiophene-2,2a(7bH)-dicarboxylic acid, 1-(1-pyrrolidinyl)-, dimethyl ester; NSC 380292; AC1L7WS8; BDBM50184086; Benzo[b]cyclobuta[d]thiophene-2, 2a,7b-dihydro-1-(1-pyrrolyl)-, dimethyl ester; (R,R/S,S)-dimethyl-1-(1-piperidynyl)cyclobuta[b][1]benzothiophene-2,2a(7bH)-dicarboxylate; dimethyl 1-pyrrolidin-1-yl-7bH-cyclobuta[b][1]benzothiole-2,2a-dicarboxylate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H19NO4S
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| Canonical SMILES |
COC(=O)C1=C(C2C1(SC3=CC=CC=C23)C(=O)OC)N4CCCC4
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| InChI |
1S/C18H19NO4S/c1-22-16(20)14-15(19-9-5-6-10-19)13-11-7-3-4-8-12(11)24-18(13,14)17(21)23-2/h3-4,7-8,13H,5-6,9-10H2,1-2H3
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| InChIKey |
WEPFRJIQIIGTEM-UHFFFAOYSA-N
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| CAS Number |
CAS 89110-18-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Inhibitor | [1] |
| References | Top | |||
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| REF 1 | New HIV-1 reverse transcriptase inhibitors based on a tricyclic benzothiophene scaffold: synthesis, resolution, and inhibitory activity. Bioorg Med Chem Lett. 2006 Jun 1;16(11):3034-8. | |||
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