Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03PLH
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| Former ID |
DIB021101
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| Drug Name |
U46619
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| Synonyms |
(Z)-7-[(1S,4R,5R,6S)-5-[(E,3S)-3-Hydroxyoct-1-enyl]-3-oxabicyclo[221]heptan-6-yl]hept-5-enoic acid; U 46619; MLS000028857; CHEMBL521784; U-46619; 56985-40-1; SMR000058897; (5Z)-7-[(1R,4S,5S,6R)-6-[(1E,3S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[221]hept-5-yl]-5-heptenoic acid; 9a,11a-Methanoepoxy-15-hydroxyprosta-5,13-dienoic acid; 9,11-Methanoepoxy PGH2; 11alpha,9alpha-epoxymethano-PGH2; 9alpha-PGM; (Z)-7-[(1S,4R,5R,6S)-5-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxabicyclo[221]heptan-6-yl]hept-5-enoic acid; 9alpha,11alpha-Methanoepoxy-PGF2alpha; Opera_ID_380; [3H]U46619; 9,11-Dideoxy-9alpha,11alpha-methanoepoxy PGF2alpha; U 46619
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL
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| Formula |
C21H34O4
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| Canonical SMILES |
CCCCCC(C=CC1C2CC(C1CC=CCCCC(=O)O)CO2)O
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| InChI |
1S/C21H34O4/c1-2-3-6-9-17(22)12-13-19-18(16-14-20(19)25-15-16)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16-,17+,18+,19-,20-/m1/s1
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| InChIKey |
LQANGKSBLPMBTJ-BRSNVKEHSA-N
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| CAS Number |
CAS 56985-40-1
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1974). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1888). | |||
| REF 3 | The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta. 2000 Jan 17;1483(2):285-93. | |||
| REF 4 | Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2. Br J Pharmacol. 2002 Dec;137(8):1163-72. | |||
| REF 5 | Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. Eur J Pharmacol. 1997 Dec 11;340(2-3):227-41. | |||
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