Drug Information
Drug General Information | Top | |||
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Drug ID |
D03PSY
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Former ID |
DNC009986
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Drug Name |
3 9-DIHYDRO-N-DESMETHYL-N-ISOPROPYLERYTHROMYCIN A
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Synonyms |
CHEMBL584549; 3 9-dihydro-N-desmethyl-N-isopropylerythromycin A; SCHEMBL13681692
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C39H73NO13
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Canonical SMILES |
CCC1C(C(C(C(C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C(C)C)O)(C)O)C)O)C)O)(C)O
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InChI |
1S/C39H73NO13/c1-15-27-39(12,47)32(43)22(6)29(41)20(4)17-37(10,46)34(53-36-30(42)26(16-21(5)49-36)40(13)19(2)3)23(7)31(24(8)35(45)51-27)52-28-18-38(11,48-14)33(44)25(9)50-28/h19-34,36,41-44,46-47H,15-18H2,1-14H3/t20-,21-,22+,23+,24-,25+,26+,27-,28+,29+,30-,31+,32-,33+,34-,36+,37-,38-,39-/m1/s1
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InChIKey |
RXJCJWPPKSQMAS-IRNFSOKPSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Voltage-gated potassium channel Kv11.1 (KCNH2) | Target Info | Inhibitor | [1] |
Pathwhiz Pathway | Muscle/Heart Contraction | |||
Reactome | Voltage gated Potassium channels | |||
WikiPathways | SIDS Susceptibility Pathways | |||
Hematopoietic Stem Cell Differentiation | ||||
Potassium Channels |
References | Top | |||
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REF 1 | 9-Dihydroerythromycin ethers as motilin agonists--developing structure-activity relationships for potency and safety. Bioorg Med Chem. 2010 Nov 1;18(21):7651-8. |
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