Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03QLG
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| Former ID |
DNC000398
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| Drug Name |
CEP1347
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| Synonyms |
AC1L31ZX; SCHEMBL1649555; ZINC103589452; DB05403
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| Drug Type |
Small molecular drug
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| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Phase 2/3 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C33H33N3O5S2
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| Canonical SMILES |
CCSCC1=CC2=C(C=C1)N3C4CC(C(O4)(N5C6=C(C=C(C=C6)CSCC)C7=C8CNC(=O)C8=C2C3=C75)C)(C(=O)OC)O
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| InChI |
1S/C33H33N3O5S2/c1-5-42-15-17-7-9-22-19(11-17)26-27-21(14-34-30(27)37)25-20-12-18(16-43-6-2)8-10-23(20)36-29(25)28(26)35(22)24-13-33(39,31(38)40-4)32(36,3)41-24/h7-12,24,39H,5-6,13-16H2,1-4H3,(H,34,37)/t24-,32+,33+/m1/s1
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| InChIKey |
SCMLRESZJCKCTC-KMYQRJGFSA-N
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| CAS Number |
CAS 156177-65-0
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Mixed lineage kinase 1 (MAP3K9) | Target Info | Inhibitor | [2] |
| WikiPathways | Insulin Signaling | |||
| p38 MAPK Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Targeting the JNK signaling pathway for stroke and Parkinson's diseases therapy. Curr Drug Targets CNS Neurol Disord. 2005 Feb;4(1):63-7. | |||
| REF 2 | Pharmacological inhibitors of MAPK pathways. Trends Pharmacol Sci. 2002 Jan;23(1):40-5. | |||
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