Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03RHZ
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| Former ID |
DIB001484
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| Drug Name |
MDL-27192
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| Synonyms |
3-(4-Chlorophenyl)-4-ethyl-1H-1,2,4-triazol-5(4H)-one; 5-(4-Chlorophenyl)-4-ethyl-3,4-dihydro-2H-1,2,4-triazol-3-one
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| Indication | Epileptic seizures [ICD-11: 8A61-8A6Z; ICD-9: 345.9, 780.3] | Phase 2 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H10ClN3O
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| Canonical SMILES |
CCN1C(=NNC1=O)C2=CC=C(C=C2)Cl
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| InChI |
1S/C10H10ClN3O/c1-2-14-9(12-13-10(14)15)7-3-5-8(11)6-4-7/h3-6H,2H2,1H3,(H,13,15)
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| InChIKey |
PXINDYJACXPZIN-UHFFFAOYSA-N
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| CAS Number |
CAS 31409-32-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Modulator | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005914) | |||
| REF 2 | Preclinical characterization of MDL 27,192 as a potential broad spectrum anticonvulsant agent with neuroprotective properties. Epilepsy Res. 1997 Apr;27(1):41-54. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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