Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03SDH
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| Former ID |
DIB009624
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| Drug Name |
Siratiazem
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| Synonyms |
LR-A-113
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| Drug Type |
Small molecular drug
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| Indication | Angina pectoris [ICD-11: BA40; ICD-9: 413] | Terminated | [1] | |
| Company |
Istituto Lusofarmaco D`Italia SpA
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H30N2O4S
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| Canonical SMILES |
CC(C)N(C)CCN1C2=CC=CC=C2SC(C(C1=O)OC(=O)C)C3=CC=C(C=C3)OC
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| InChI |
1S/C24H30N2O4S/c1-16(2)25(4)14-15-26-20-8-6-7-9-21(20)31-23(22(24(26)28)30-17(3)27)18-10-12-19(29-5)13-11-18/h6-13,16,22-23H,14-15H2,1-5H3/t22-,23+/m1/s1
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| InChIKey |
VVZILLNNYUUOIY-PKTZIBPZSA-N
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| CAS Number |
CAS 138778-28-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001949) | |||
| REF 2 | Comparison of the effects of diltiazem and its analogue siratiazem on contractility in arteries, ileum and cardiac muscle. J Auton Pharmacol. 1995 Apr;15(2):107-13. | |||
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