Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03UQM
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| Former ID |
DAP000886
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| Drug Name |
Retapamulin
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| Synonyms |
Altabax; Altargo; SB 275833; Altabax (Glaxo); Altabax (TN); Altargo (TN); Retapamulin (USAN/INN)
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| Drug Type |
Small molecular drug
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| Indication | Impetigo [ICD-11: 1B72; ICD-10: L01, L01.0; ICD-9: 684] | Approved | [1] | |
| Therapeutic Class |
Antibiotics
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| Company |
GlaxoSmithKline
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| Structure |
 |
Download2D MOL |
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| Formula |
C30H47NO4S
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| Canonical SMILES |
CC1CCC23CCC(=O)C2C1(C(CC(C(C3C)O)(C)C=C)OC(=O)CSC4CC5CCC(C4)N5C)C
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| InChI |
1S/C30H47NO4S/c1-7-28(4)16-24(35-25(33)17-36-22-14-20-8-9-21(15-22)31(20)6)29(5)18(2)10-12-30(19(3)27(28)34)13-11-23(32)26(29)30/h7,18-22,24,26-27,34H,1,8-17H2,2-6H3/t18-,19+,20-,21+,22?,24-,26+,27+,28-,29+,30+/m1/s1
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| InChIKey |
STZYTFJPGGDRJD-FJJJPKKESA-N
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| CAS Number |
CAS 224452-66-8
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:166679
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| ADReCS Drug ID | BADD_D01928 | |||
| SuperDrug ATC ID |
D06AX13
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial 50S ribosomal RNA (Bact 50S rRNA) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 022055. | |||
| REF 2 | Retapamulin inhibition of translation and 50S ribosomal subunit formation in Staphylococcus aureus cells. Antimicrob Agents Chemother. 2007 Sep;51(9):3385-7. | |||
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