Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03VUU
|
|||
| Former ID |
DNC010210
|
|||
| Drug Name |
2-(9,10-dihydroanthracen-9-yl)-N-methylethanamine
|
|||
| Synonyms |
CHEMBL595158; BDBM35924; 9,10-dihydroanthracene(DHA), 2b
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C17H19N
|
|||
| Canonical SMILES |
CNCCC1C2=CC=CC=C2CC3=CC=CC=C13
|
|||
| InChI |
1S/C17H19N/c1-18-11-10-17-15-8-4-2-6-13(15)12-14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3
|
|||
| InChIKey |
PVWQFOKNAQZORV-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| Histamine H1 receptor (H1R) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Histamine H1 receptor mediated signaling pathway | |||
| 5HT2 type receptor mediated signaling pathway | ||||
| Reactome | Histamine receptors | |||
| G alpha (q) signalling events | ||||
| Serotonin receptors | ||||
| WikiPathways | Monoamine GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| IL-4 Signaling Pathway | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| Serotonin Receptor 2 and STAT3 Signaling | ||||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, structure-affinity relationships, and modeling of AMDA analogs at 5-HT2A and H1 receptors: structural factors contributing to selectivity. Bioorg Med Chem. 2009 Sep 15;17(18):6496-504. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.