Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D03ZUM
|
|||
Former ID |
DNC014635
|
|||
Drug Name |
Tert-butyloxy carbonyl-D-Phe-pro-Arg-H
|
|||
Synonyms |
CHEMBL104472; LY-178207; tert-butyloxy carbonyl-D-Phe-pro-Arg-H; AC1OCEOE; SCHEMBL7371676; BDBM50046360; BDBM50029511; {1-Benzyl-2-[2-(1-formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester; {(R)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester; tert-butyl N-[(2R)-1-[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]carbamate
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C25H38N6O5
|
|||
Canonical SMILES |
CC(C)(C)OC(=O)NC(CC1=CC=CC=C1)C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C=O
|
|||
InChI |
1S/C25H38N6O5/c1-25(2,3)36-24(35)30-19(15-17-9-5-4-6-10-17)22(34)31-14-8-12-20(31)21(33)29-18(16-32)11-7-13-28-23(26)27/h4-6,9-10,16,18-20H,7-8,11-15H2,1-3H3,(H,29,33)(H,30,35)(H4,26,27,28)/t18-,19+,20-/m0/s1
|
|||
InChIKey |
JDXUSWQJCGTBLN-ZCNNSNEGSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Cationic trypsinogen (PRSS1) | Target Info | Inhibitor | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Pancreatic secretion | ||||
Protein digestion and absorption | ||||
Influenza A | ||||
Reactome | Activation of Matrix Metalloproteinases | |||
Cobalamin (Cbl, vitamin B12) transport and metabolism | ||||
WikiPathways | Activation of Matrix Metalloproteinases |
References | Top | |||
---|---|---|---|---|
REF 1 | Structure-activity study of tripeptide thrombin inhibitors using alpha-alkyl amino acids and other conformationally constrained amino acid substitu... J Med Chem. 1995 Oct 27;38(22):4446-53. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.