Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04BUH
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| Former ID |
DCL000753
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| Drug Name |
Cizolirtine
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| Synonyms |
Cizolirtine [INN]; N,N-dimethyl-2-[(2-methylpyrazol-3-yl)-phenylmethoxy]ethanamine; N,N-dimethyl-2-[(R)-(2-methylpyrazol-3-yl)-phenylmethoxy]ethanamine
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| Drug Type |
Small molecular drug
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| Indication | Neuropathic pain [ICD-11: 8E43.0] | Phase 2 | [1] | |
| Therapeutic Class |
Analgesics
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| Company |
Esteve Laboratories
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| Structure |
 |
Download2D MOL |
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| Formula |
C15H21N3O
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| Canonical SMILES |
CN1C(=CC=N1)C(C2=CC=CC=C2)OCCN(C)C
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| InChI |
1S/C15H21N3O/c1-17(2)11-12-19-15(13-7-5-4-6-8-13)14-9-10-16-18(14)3/h4-10,15H,11-12H2,1-3H3
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| InChIKey |
DCMJBKFKXGPPMT-UHFFFAOYSA-N
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| CAS Number |
CAS 142155-43-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcitonin gene-related peptide 1 (CALCA) | Target Info | Inhibitor | [1] |
| Reactome | G alpha (s) signalling events | |||
| Calcitonin-like ligand receptors | ||||
| WikiPathways | Myometrial Relaxation and Contraction Pathways | |||
| Endothelin Pathways | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs in neuropathic pain. Expert Opin Emerg Drugs. 2007 Mar;12(1):113-26. | |||
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