Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04BXA
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| Drug Name |
Pyrazole derivative 32
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| Synonyms |
PMID26161824-Compound-46
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| Drug Type |
Small molecular drug
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| Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Patented | [1] | |
| Company |
GREEN CROSS CORPORATION LEE, Sung-Han SEO, Hee Jeong LEE, Jinhwa KIM, Min-ah KIM, Jeong Min KANG, Suk Youn AHN, Kwang-Woo LEE, Suk Ho
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| Structure |
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Download2D MOL |
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| Formula |
C25H22BrCl2N5OS
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| Canonical SMILES |
CC(C)(C)C1=NN=C(S1)C2=NN(C(=C2C(=O)NC3CC3)C4=CC=C(C=C4)Br)C5=C(C=C(C=C5)Cl)Cl
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| InChI |
1S/C25H22BrCl2N5OS/c1-25(2,3)24-31-30-23(35-24)20-19(22(34)29-16-9-10-16)21(13-4-6-14(26)7-5-13)33(32-20)18-11-8-15(27)12-17(18)28/h4-8,11-12,16H,9-10H2,1-3H3,(H,29,34)
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| InChIKey |
GBQKLVGYQWGQEF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 1 (CB1) | Target Info | Antagonist | [1] |
| Target's Patent Info | Cannabinoid receptor 1 (CB1) | Target's Patent Info | [1] | |
| KEGG Pathway | Rap1 signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | ||||
| Panther Pathway | Endogenous cannabinoid signaling | |||
| Pathway Interaction Database | N-cadherin signaling events | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| BDNF signaling pathway | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents. Expert Opin Ther Pat. 2015 Oct;25(10):1093-116. | |||
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