Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04BXL
|
|||
| Former ID |
DNC006238
|
|||
| Drug Name |
2-morpholino-7-(2-phenylethynyl)-4H-chromen-4-one
|
|||
| Synonyms |
CHEMBL95923
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H17NO3
|
|||
| Canonical SMILES |
C1COCCN1C2=CC(=O)C3=C(O2)C=C(C=C3)C#CC4=CC=CC=C4
|
|||
| InChI |
1S/C21H17NO3/c23-19-15-21(22-10-12-24-13-11-22)25-20-14-17(8-9-18(19)20)7-6-16-4-2-1-3-5-16/h1-5,8-9,14-15H,10-13H2
|
|||
| InChIKey |
INSPUQMNGZSNFZ-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3A (PDE3A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Purine metabolism | |||
| cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| WikiPathways | miR-targeted genes in muscle cell - TarBase | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity. Bioorg Med Chem Lett. 2006 Feb 15;16(4):969-73. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.