Drug Information
Drug General Information | Top | |||
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Drug ID |
D04GOO
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Former ID |
DNC010275
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Drug Name |
N1,N3-bis(3-methoxybenzyl)isophthalamide
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Synonyms |
CHEMBL605201; N1,N3-bis(3-methoxybenzyl)isophthalamide; SCHEMBL5332068
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C24H24N2O4
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Canonical SMILES |
COC1=CC=CC(=C1)CNC(=O)C2=CC(=CC=C2)C(=O)NCC3=CC(=CC=C3)OC
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InChI |
1S/C24H24N2O4/c1-29-21-10-3-6-17(12-21)15-25-23(27)19-8-5-9-20(14-19)24(28)26-16-18-7-4-11-22(13-18)30-2/h3-14H,15-16H2,1-2H3,(H,25,27)(H,26,28)
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InChIKey |
XDBOLPFDJWTESQ-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Matrix metalloproteinase-13 (MMP-13) | Target Info | Inhibitor | [1] |
NetPath Pathway | IL1 Signaling Pathway | |||
Panther Pathway | Alzheimer disease-presenilin pathway | |||
Plasminogen activating cascade | ||||
Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | |||
Reactome | Collagen degradation | |||
Degradation of the extracellular matrix | ||||
Activation of Matrix Metalloproteinases | ||||
Assembly of collagen fibrils and other multimeric structures | ||||
WikiPathways | Endochondral Ossification | |||
Activation of Matrix Metalloproteinases | ||||
Oncostatin M Signaling Pathway | ||||
AGE/RAGE pathway | ||||
Matrix Metalloproteinases |
References | Top | |||
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REF 1 | Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment ... Bioorg Med Chem Lett. 2010 Jan 15;20(2):576-80. |
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