Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04HQK
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| Former ID |
DNC012155
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| Drug Name |
N-(5-Sulfamoyl-[1,3,4]thiadiazol-2-yl)-benzamide
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| Synonyms |
NSC698990; CHEMBL281376; N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)benzamide; 86029-44-9; N-(2-sulfamoyl-1,3,4-thiadiazol-5-yl)benzamide; Benzamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-; SCHEMBL9795960; AC1L997Y; BDBM16669; CTK2I3789; DTXSID30327878; ZINC5925092; heterocyclic sulfonamide compound 34; AKOS030579978; NSC-698990; NCI60_035393; LS-25666; 2-benzoylamino-1,3,4-thiadiazole 5-sulfonamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H8N4O3S2
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| Canonical SMILES |
C1=CC=C(C=C1)C(=O)NC2=NN=C(S2)S(=O)(=O)N
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| InChI |
1S/C9H8N4O3S2/c10-18(15,16)9-13-12-8(17-9)11-7(14)6-4-2-1-3-5-6/h1-5H,(H2,10,15,16)(H,11,12,14)
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| InChIKey |
PMNNJWNEWDGYIV-UHFFFAOYSA-N
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| CAS Number |
CAS 86029-44-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase IV (CA-IV) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties. J Med Chem. 2002 Jan 17;45(2):312-20. | |||
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