Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04ITR
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| Drug Name |
PMID26868298-compound-N3
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| Synonyms |
PMID26868298-C-N3
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| Drug Type |
Small molecular drug
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| Indication | Middle East Respiratory Syndrome (MERS) [ICD-11: 1D64] | Preclinical | [1] | |
| Severe acute respiratory syndrome (SARS) [ICD-11: 1D65] | Preclinical | [1] | ||
| Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Investigative | [2] | ||
| Therapeutic Class |
Antiviral Agents
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | COVID-19 papain-like proteinase (PL-PRO) | Target Info | Inhibitor | [2] |
| MERS-CoV 3C-like proteinase (3CLpro) | Target Info | Inhibitor | [1] | |
| SARS-CoV 3C-like protease (3CLpro) | Target Info | Inhibitor | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47. | |||
| REF 2 | Structure of Mpro from COVID-19 virus and discovery of its inhibitors. Nature. 2020 Apr 9. | |||
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