Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04JIH
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| Drug Name |
PMID27376512-Compound-Table1Example11
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| Drug Type |
Small molecular drug
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| Company |
IKERCHEM S L [ESUNIV DEL PA S VASCO [ES]
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H21NO9
|
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| Canonical SMILES |
COC1=CC2=C(C(=C1)OC)C(=CN2CC(=O)C3=C(C(=C(C=C3)O)O)O)C4=C(C(=C(C=C4)O)O)O
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| InChI |
1S/C24H21NO9/c1-33-11-7-15-20(19(8-11)34-2)14(12-3-5-16(26)23(31)21(12)29)9-25(15)10-18(28)13-4-6-17(27)24(32)22(13)30/h3-9,26-27,29-32H,10H2,1-2H3
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| InChIKey |
GBDRNHMXDAEPNN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA [cytosine-5]-methyltransferase 1 (DNMT1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | DNA [cytosine-5]-methyltransferase 1 (DNMT1) | Target's Patent Info | [1] | |
| KEGG Pathway | Cysteine and methionine metabolism | |||
| Metabolic pathways | ||||
| MicroRNAs in cancer | ||||
| Pathwhiz Pathway | Methionine Metabolism | |||
| Pathway Interaction Database | Regulation of retinoblastoma protein | |||
| Reactome | PRC2 methylates histones and DNA | |||
| NoRC negatively regulates rRNA expression | ||||
| DNA methylation | ||||
| WikiPathways | Trans-sulfuration and one carbon metabolism | |||
| Retinoblastoma (RB) in Cancer | ||||
| One Carbon Metabolism | ||||
| Trans-sulfuration pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | DNA methyltransferase inhibitors: an updated patent review (2012-2015).Expert Opin Ther Pat. 2016 Sep;26(9):1017-30. | |||
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