Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04KAZ
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| Former ID |
DNC007981
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| Drug Name |
1-phenyl-3-(phenylsulfonyl)propan-1-one
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| Synonyms |
1-phenyl-3-(phenylsulfonyl)propan-1-one; CHEMBL240292; ZINC28874843
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H14O3S
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| Canonical SMILES |
C1=CC=C(C=C1)C(=O)CCS(=O)(=O)C2=CC=CC=C2
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| InChI |
1S/C15H14O3S/c16-15(13-7-3-1-4-8-13)11-12-19(17,18)14-9-5-2-6-10-14/h1-10H,11-12H2
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| InChIKey |
IOTOILGYCOMTGK-UHFFFAOYSA-N
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| CAS Number |
CAS 65885-28-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolism of xenobiotics by cytochrome P450 | ||||
| Metabolic pathways | ||||
| Chemical carcinogenesis | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| Metabolism of steroid hormones and vitamin D | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | beta-Keto sulfones as inhibitors of 11beta-hydroxysteroid dehydrogenase type I and the mechanism of action. Bioorg Med Chem. 2007 Jul 1;15(13):4396-405. | |||
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