Drug Information
Drug General Information | Top | |||
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Drug ID |
D04KDB
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Former ID |
DNC004499
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Drug Name |
6-Imidazol-1-yl-3,4-dihydro-1H-quinolin-2-one
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Synonyms |
CHEMBL17516; 119924-94-6; 3,4-dihydro-6-(1H-imidazol-1-yl)quinolin-2(1H)-one; 2(1H)-Quinolinone, 3,4-dihydro-6-(1H-imidazol-1-yl)-; ACMC-20momi; 6-Imidazol-1-yl-3,4-dihydro-1H-quinolin-2-one; SCHEMBL10463333; CTK0F9353; DTXSID20551867; BDMKPUAZENLRDY-UHFFFAOYSA-N; BDBM50000309; 6-(imidazol-1-yl)-3,4-dihydrocarbostyril
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H11N3O
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Canonical SMILES |
C1CC(=O)NC2=C1C=C(C=C2)N3C=CN=C3
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InChI |
1S/C12H11N3O/c16-12-4-1-9-7-10(2-3-11(9)14-12)15-6-5-13-8-15/h2-3,5-8H,1,4H2,(H,14,16)
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InChIKey |
BDMKPUAZENLRDY-UHFFFAOYSA-N
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CAS Number |
CAS 119924-94-6
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Phosphodiesterase 3A (PDE3A) | Target Info | Inhibitor | [1] |
KEGG Pathway | Purine metabolism | |||
cGMP-PKG signaling pathway | ||||
cAMP signaling pathway | ||||
Morphine addiction | ||||
Reactome | cGMP effects | |||
G alpha (s) signalling events | ||||
WikiPathways | miR-targeted genes in muscle cell - TarBase | |||
miR-targeted genes in lymphocytes - TarBase |
References | Top | |||
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REF 1 | 3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase. J Med Chem. 1992 Feb 21;35(4):620-8. |
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