Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04QNI
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| Former ID |
DNC014661
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| Drug Name |
(O10eq)-beta-alanyl-anhydro-ryanodine
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| Synonyms |
CHEMBL28261; (O10eq)-beta-alanyl-anhydro-ryanodine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C28H38N2O9
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| Canonical SMILES |
CC1CCC2(C3(CC(=O)OC2(C1OC(=O)CCN)C4(C3(C(C(=C4C)C(C)C)OC(=O)C5=CC=CN5)O)O)C)O
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| InChI |
1S/C28H38N2O9/c1-14(2)20-16(4)26(35)27(36,22(20)38-23(33)17-7-6-12-30-17)24(5)13-19(32)39-28(26)21(37-18(31)9-11-29)15(3)8-10-25(24,28)34/h6-7,12,14-15,21-22,30,34-36H,8-11,13,29H2,1-5H3/t15?,21-,22-,24+,25?,26?,27?,28?/m1/s1
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| InChIKey |
NJCSEUYLWFFKSS-FCKNYIKNSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ryanodine receptor 1 (RYR1) | Target Info | Inhibitor | [1] |
| Panther Pathway | Beta1 adrenergic receptor signaling pathway | |||
| Beta2 adrenergic receptor signaling pathway | ||||
| CCKR signaling map ST | ||||
| Reactome | Stimuli-sensing channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Amino- and guanidinoacylryanodines: basic ryanodine esters with enhanced affinity for the sarcoplasmic reticulum Ca(2+)-release channel. J Med Chem. 1993 May 14;36(10):1319-23. | |||
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