Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04SDD
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| Former ID |
DNC007773
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| Drug Name |
N6-(3-Iodobenzyl)-2'-O-methyladenosine
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| Synonyms |
CHEMBL428377; BDBM50215115
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H20IN5O4
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| Canonical SMILES |
COC1C(C(OC1N2C=NC3=C(N=CN=C32)NCC4=CC(=CC=C4)I)CO)O
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| InChI |
1S/C18H20IN5O4/c1-27-15-14(26)12(7-25)28-18(15)24-9-23-13-16(21-8-22-17(13)24)20-6-10-3-2-4-11(19)5-10/h2-5,8-9,12,14-15,18,25-26H,6-7H2,1H3,(H,20,21,22)/t12-,14-,15-,18-/m1/s1
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| InChIKey |
OATZXEKAXIIRDK-SCFUHWHPSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A3 receptor (ADORA3) | Target Info | Inhibitor | [1] |
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands. Bioorg Med Chem. 2007 Aug 15;15(16):5440-7. | |||
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