Drug Information
Drug General Information | Top | |||
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Drug ID |
D04SHH
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Former ID |
DIB009278
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Drug Name |
TC-6499-12
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Synonyms |
TC-6499; Alpha 4 beta 2 neuronal nicotinic modulator (pain/IBS), Targacept
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Indication | Irritable bowel syndrome [ICD-11: DD91.0; ICD-10: K55-K64, K58; ICD-9: 564.1, 787.91] | Phase 2 | [1] | |
Company |
Targacept Inc
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Target and Pathway | Top | |||
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Target(s) | Neuronal acetylcholine receptor alpha-4/beta-2 (CHRNA4/B2) | Target Info | Modulator | [2] |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01149200) Proof-of-Principle Study of TC-6499 in the Treatment of Constipation Predominant Irritable Bowel Syndrome (IBS). U.S. National Institutes of Health. | |||
REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. |
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