Drug Information
Drug General Information | Top | |||
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Drug ID |
D04TXB
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Former ID |
DIB014552
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Drug Name |
Ceplene/Peg-Intron/Rebetol
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Synonyms |
Histamine dihydrochloride/peg-interferon alfa-2b/ribavirin
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Indication | Hepatitis C virus infection [ICD-11: 1E51.1; ICD-10: B18.2] | Investigative | [1] | |
Company |
Maxim Pharmaceuticals
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Target and Pathway | Top | |||
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Target(s) | Interferon alpha/beta receptor 1 (IFNAR1) | Target Info | Modulator | [1] |
KEGG Pathway | Cytokine-cytokine receptor interaction | |||
PI3K-Akt signaling pathway | ||||
Osteoclast differentiation | ||||
Toll-like receptor signaling pathway | ||||
Jak-STAT signaling pathway | ||||
Natural killer cell mediated cytotoxicity | ||||
Hepatitis C | ||||
Hepatitis B | ||||
Measles | ||||
Influenza A | ||||
Herpes simplex infection | ||||
NetPath Pathway | TCR Signaling Pathway | |||
Leptin Signaling Pathway | ||||
Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
Pathway Interaction Database | Downstream signaling in naï | |||
Reactome | Interferon alpha/beta signaling | |||
Regulation of IFNA signaling | ||||
WikiPathways | Toll-like receptor signaling pathway | |||
Interferon type I signaling pathways | ||||
Interferon alpha/beta signaling | ||||
Regulation of toll-like receptor signaling pathway | ||||
Osteoclast Signaling |
References | Top | |||
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REF 1 | Resistance to mericitabine, a nucleoside analogue inhibitor of HCV RNA-dependent RNA polymerase. Antivir Ther. 2012;17(3):411-23. |
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