Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04URI
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| Former ID |
DIB019576
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| Drug Name |
PMID21277783C7
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| Synonyms |
citibrasine; Citibrasine; Citbrasine; GTPL8561; BDBM50336482
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C17H17NO6
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| Canonical SMILES |
CN1C2=C(C=CC=C2O)C(=O)C3=C1C(=C(C(=C3O)OC)OC)OC
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| InChI |
1S/C17H17NO6/c1-18-11-8(6-5-7-9(11)19)13(20)10-12(18)15(22-2)17(24-4)16(23-3)14(10)21/h5-7,19,21H,1-4H3
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| InChIKey |
QYPQTPVQPNLXHV-UHFFFAOYSA-N
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| CAS Number |
CAS 86680-34-4
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cathepsin V (CTSV) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Lysosome | |||
| Reactome | Endosomal/Vacuolar pathway | |||
| Degradation of the extracellular matrix | ||||
| Activation of Matrix Metalloproteinases | ||||
| Trafficking and processing of endosomal TLR | ||||
| Assembly of collagen fibrils and other multimeric structures | ||||
| MHC class II antigen presentation | ||||
| WikiPathways | Endochondral Ossification | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Acridone alkaloids as potent inhibitors of cathepsin V. Bioorg Med Chem. 2011 Feb 15;19(4):1477-81. | |||
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