Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04UYO
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| Former ID |
DNC011959
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| Drug Name |
HMR-1556
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| Synonyms |
GTPL2590
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C18H26F3NO5S
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| Canonical SMILES |
CCS(=O)(=O)N(C)C1C(C(OC2=C1C=C(C=C2)OCCCC(F)(F)F)(C)C)O
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| InChI |
1S/C18H26F3NO5S/c1-5-28(24,25)22(4)15-13-11-12(26-10-6-9-18(19,20)21)7-8-14(13)27-17(2,3)16(15)23/h7-8,11,15-16,23H,5-6,9-10H2,1-4H3/t15-,16+/m0/s1
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| InChIKey |
YBZQPPIQXNWGEX-JKSUJKDBSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated potassium channel Kv7.1 (KCNQ1) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Adrenergic signaling in cardiomyocytes | |||
| Cholinergic synapse | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Protein digestion and absorption | ||||
| Vibrio cholerae infection | ||||
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Reactome | Voltage gated Potassium channels | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Potassium Channels | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| TarBasePathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2590). | |||
| REF 2 | Selective optimization of side activities: another way for drug discovery. J Med Chem. 2004 Mar 11;47(6):1303-14. | |||
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