Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04YKV
|
|||
| Drug Name |
PMID28454500-Compound-93
|
|||
| Drug Type |
Small molecular drug
|
|||
| Company |
THE HAMNER INSTITUTES
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C8H10N2O
|
|||
| Canonical SMILES |
CC1=CC=C(C=C1)C(=O)NN
|
|||
| InChI |
1S/C8H10N2O/c1-6-2-4-7(5-3-6)8(11)10-9/h2-5H,9H2,1H3,(H,10,11)
|
|||
| InChIKey |
MFFVZXOPRXMVET-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 3619-22-5
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nuclear factor erythroid 2-related factor 2 (Nrf2) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Nuclear factor erythroid 2-related factor 2 (Nrf2) | Target's Patent Info | [1] | |
| KEGG Pathway | Protein processing in endoplasmic reticulum | |||
| NetPath Pathway | IL5 Signaling Pathway | |||
| WikiPathways | Oxidative Stress | |||
| Transcriptional activation by NRF2 | ||||
| NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | ||||
| Aryl Hydrocarbon Receptor Pathway | ||||
| Mesodermal Commitment Pathway | ||||
| Aryl Hydrocarbon Receptor | ||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
| Arylhydrocarbon receptor (AhR) signaling pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Recent progress in the development of small molecule Nrf2 modulators: a patent review (2012-2016).Expert Opin Ther Pat. 2017 Jul;27(7):763-785. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.