Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D04ZLC
|
|||
Drug Name |
N-(arylalkyl)-1H-indole-2-sulfonic acid amide derivative 1
|
|||
Synonyms |
PMID26161824-Compound-186
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Patented | [1] | |
Company |
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN GREIG, lain Robert ROSS, Ruth Alexandra PERTWEE, Roger Guy TREMBLEAU, Laurent Alain Claude ABDEL-RAHMAN, Mostafa Hamed BAILLIE, Gemma Louise
|
|||
Structure |
Download2D MOL |
|||
Formula |
C17H18N2O4S
|
|||
Canonical SMILES |
COC1=CC=C(C=C1)CNS(=O)(=O)C2=CC3=C(N2)C=CC(=C3)OC
|
|||
InChI |
1S/C17H18N2O4S/c1-22-14-5-3-12(4-6-14)11-18-24(20,21)17-10-13-9-15(23-2)7-8-16(13)19-17/h3-10,18-19H,11H2,1-2H3
|
|||
InChIKey |
ZYAIUNMZKGHCRV-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Cannabinoid receptor 1 (CB1) | Target Info | Antagonist | [1] |
Target's Patent Info | Cannabinoid receptor 1 (CB1) | Target's Patent Info | [1] | |
KEGG Pathway | Rap1 signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Retrograde endocannabinoid signaling | ||||
Panther Pathway | Endogenous cannabinoid signaling | |||
Pathway Interaction Database | N-cadherin signaling events | |||
Reactome | Class A/1 (Rhodopsin-like receptors) | |||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Small Ligand GPCRs | ||||
BDNF signaling pathway | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
---|---|---|---|---|
REF 1 | A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents. Expert Opin Ther Pat. 2015 Oct;25(10):1093-116. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.