Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04ZOI
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| Former ID |
DNC011704
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| Drug Name |
4-(8-Phenyl-oct-3-ynyl)-1H-imidazole
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| Synonyms |
CHEMBL14811; 4-(8-Phenyl-oct-3-ynyl)-1H-imidazole; SCHEMBL7621857; ZINC13795232; BDBM50070216
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H20N2
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| Canonical SMILES |
C1=CC=C(C=C1)CCCCC#CCCC2=CN=CN2
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| InChI |
1S/C17H20N2/c1(2-4-9-13-17-14-18-15-19-17)3-6-10-16-11-7-5-8-12-16/h5,7-8,11-12,14-15H,1,3,6,9-10,13H2,(H,18,19)
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| InChIKey |
MSBRTBBFZFRZEJ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | New acetylene based histamine H3 receptor antagonists derived from the marine natural product verongamine. Bioorg Med Chem Lett. 1998 May 19;8(10):1133-8. | |||
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