Drug Information
Drug General Information | Top | |||
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Drug ID |
D05DBJ
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Former ID |
DNC009410
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Drug Name |
2-(4-methoxybenzylthio)-6-methylpyrimidin-4-ol
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Canonical SMILES |
CC1=CC(=O)N=C(N1)SCC2=CC=C(C=C2)OC
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Matrix metalloproteinase-13 (MMP-13) | Target Info | Inhibitor | [1] |
NetPath Pathway | IL1 Signaling Pathway | |||
Panther Pathway | Alzheimer disease-presenilin pathway | |||
Plasminogen activating cascade | ||||
Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | |||
Reactome | Collagen degradation | |||
Degradation of the extracellular matrix | ||||
Activation of Matrix Metalloproteinases | ||||
Assembly of collagen fibrils and other multimeric structures | ||||
WikiPathways | Endochondral Ossification | |||
Activation of Matrix Metalloproteinases | ||||
Oncostatin M Signaling Pathway | ||||
AGE/RAGE pathway | ||||
Matrix Metalloproteinases |
References | Top | |||
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REF 1 | Ranking the selectivity of PubChem screening hits by activity-based protein profiling: MMP13 as a case study. Bioorg Med Chem. 2009 Feb 1;17(3):1101-8. |
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