Drug Information
Drug General Information | Top | |||
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Drug ID |
D05GQK
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Former ID |
DIB020812
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Drug Name |
R-L3
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Synonyms |
R-L364,373
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C25H20FN3O
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Canonical SMILES |
CN1C2=CC=CC=C2C(=NC(C1=O)CC3=CNC4=CC=CC=C43)C5=CC=CC=C5F
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InChI |
1S/C25H20FN3O/c1-29-23-13-7-4-10-19(23)24(18-9-2-5-11-20(18)26)28-22(25(29)30)14-16-15-27-21-12-6-3-8-17(16)21/h2-13,15,22,27H,14H2,1H3/t22-/m1/s1
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InChIKey |
CGBANSGENFERAT-JOCHJYFZSA-N
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CAS Number |
CAS 103342-82-1
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PubChem Compound ID | ||||
PubChem Substance ID | ||||
ChEBI ID |
CHEBI:34942
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Target and Pathway | Top | |||
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Target(s) | Voltage-gated potassium channel Kv7.1 (KCNQ1) | Target Info | Activator | [2] |
KEGG Pathway | Adrenergic signaling in cardiomyocytes | |||
Cholinergic synapse | ||||
Gastric acid secretion | ||||
Pancreatic secretion | ||||
Protein digestion and absorption | ||||
Vibrio cholerae infection | ||||
Pathwhiz Pathway | Muscle/Heart Contraction | |||
Reactome | Voltage gated Potassium channels | |||
WikiPathways | SIDS Susceptibility Pathways | |||
Potassium Channels | ||||
miR-targeted genes in muscle cell - TarBase | ||||
miR-targeted genes in lymphocytes - TarBase | ||||
TarBasePathway |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2595). | |||
REF 2 | A novel benzodiazepine that activates cardiac slow delayed rectifier K+ currents. Mol Pharmacol. 1998 Jul;54(1):220-30. |
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