Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05HFD
|
|||
| Former ID |
DNC004195
|
|||
| Drug Name |
7-Methyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one
|
|||
| Synonyms |
CHEMBL98738; 7-Methyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one; SCHEMBL10758549
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C11H9N3O
|
|||
| Canonical SMILES |
CC1=CC2=CC3=C(NC(=O)N3)N=C2C=C1
|
|||
| InChI |
1S/C11H9N3O/c1-6-2-3-8-7(4-6)5-9-10(12-8)14-11(15)13-9/h2-5H,1H3,(H2,12,13,14,15)
|
|||
| InChIKey |
BSAKVJKPJIQKNP-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3A (PDE3A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Purine metabolism | |||
| cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| WikiPathways | miR-targeted genes in muscle cell - TarBase | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation. J Med Chem. 1991 Sep;34(9):2906-16. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.