Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05HLQ
|
|||
| Drug Name |
Quinazoline derivative 1
|
|||
| Synonyms |
PMID25482888-Compound-68
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Company |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH PFRENGLE, Waldemar FRANK, Markus KLEIN, Thomas
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C50H56N16O4
|
|||
| Canonical SMILES |
CC#CCN1C2=C(N=C1N3CCCC(C3)N)N(C(=O)N(C2=O)CC4=NC(C5=CC=CC=C5N4)(C)CC6=NC(=NC7=CC=CC=C76)CN8C(=O)C9=C(N=C(N9CC#CC)N1CCCC(C1)N)N(C8=O)C)C
|
|||
| InChI |
1S/C50H56N16O4/c1-6-8-24-63-40-42(56-46(63)61-22-14-16-31(51)27-61)59(4)48(69)65(44(40)67)29-38-53-35-20-12-10-18-33(35)37(55-38)26-50(3)34-19-11-13-21-36(34)54-39(58-50)30-66-45(68)41-43(60(5)49(66)70)57-47(64(41)25-9-7-2)62-23-15-17-32(52)28-62/h10-13,18-21,31-32H,14-17,22-30,51-52H2,1-5H3,(H,54,58)/t31-,32-,50?/m1/s1
|
|||
| InChIKey |
CEWRYIAJQLCIAT-BZDWUGKRSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dipeptidyl peptidase 4 (DPP-4) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Dipeptidyl peptidase 4 (DPP-4) | Target's Patent Info | [1] | |
| KEGG Pathway | Protein digestion and absorption | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | DPP-4 inhibitors: a patent review (2012 - 2014).Expert Opin Ther Pat. 2015 Feb;25(2):209-36. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.