Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05ICF
|
|||
| Former ID |
DNC014569
|
|||
| Drug Name |
1,3-Di-p-tolyl-[1,3]diazetidine-2,4-dione
|
|||
| Synonyms |
CHEMBL296771; 1,3-bis(4-methylphenyl)-1,3-diazetidine-2,4-dione; 1,3-Di-p-tolyl-[1,3]diazetidine-2,4-dione; AC1MRG54; SCHEMBL19214040
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C16H14N2O2
|
|||
| Canonical SMILES |
CC1=CC=C(C=C1)N2C(=O)N(C2=O)C3=CC=C(C=C3)C
|
|||
| InChI |
1S/C16H14N2O2/c1-11-3-7-13(8-4-11)17-15(19)18(16(17)20)14-9-5-12(2)6-10-14/h3-10H,1-2H3
|
|||
| InChIKey |
AZZFGWWOGRBVOV-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cationic trypsinogen (PRSS1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Pancreatic secretion | ||||
| Protein digestion and absorption | ||||
| Influenza A | ||||
| Reactome | Activation of Matrix Metalloproteinases | |||
| Cobalamin (Cbl, vitamin B12) transport and metabolism | ||||
| WikiPathways | Activation of Matrix Metalloproteinases | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibition of serine proteases: activity of 1,3-diazetidine-2,4-diones. Bioorg Med Chem Lett. 2001 Jul 9;11(13):1691-4. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.