Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D05JET
|
|||
Former ID |
DPR000126
|
|||
Drug Name |
Remacemide
|
|||
Synonyms |
Remacemida; Remacemidum; Remacemide [INN]; FPL 12924; FPL 12924AA; FPL 14144; FPL 14145; FPL-12944AA; PR 1032-644; PR 934-423; PR1032-646; Remacemida [INN-Spanish]; Remacemidum [INN-Latin]; PR-934-423; Remacemide monohydrochloride, (+-)-isomer; (+)-2-Amino-N-(1-methyl-1,2-diphenylethyl)acetamide; (+-)-2-Amino-N-(1-methyl-1,2-diphenylethyl)acetamide; (-)-2-Amino-N-(1-methyl-1,2-diphenylethyl)acetamide; 2-amino-N-(1,2-diphenylpropan-2-yl)acetamide; 2-amino-N-(1-methyl-1,2-diphenylethyl)acetamide
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Pain [ICD-11: MG30-MG3Z] | Phase 3 | [1] | |
Company |
Astra Zeneca
|
|||
Structure |
Download2D MOL |
|||
Formula |
C17H20N2O
|
|||
Canonical SMILES |
CC(CC1=CC=CC=C1)(C2=CC=CC=C2)NC(=O)CN
|
|||
InChI |
1S/C17H20N2O/c1-17(19-16(20)13-18,15-10-6-3-7-11-15)12-14-8-4-2-5-9-14/h2-11H,12-13,18H2,1H3,(H,19,20)
|
|||
InChIKey |
YSGASDXSLKIKOD-UHFFFAOYSA-N
|
|||
CAS Number |
CAS 128298-28-2
|
|||
PubChem Compound ID | ||||
PubChem Substance ID |
6257068, 8186897, 14848312, 43117902, 49858030, 49858031, 49858032, 50787713, 57314025, 85788157, 90490603, 92729779, 103199491, 104320951, 125823975, 126682339, 129840666, 131297093, 135047599, 135203406, 135203407, 142472738, 173894588, 179080708, 179577889, 203098689, 223657235, 226516225, 249995109, 252770057
|
|||
ChEBI ID |
CHEBI:91654
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Agonist | [2], [3] |
References | Top | |||
---|---|---|---|---|
REF 1 | Block of the N-methyl-D-aspartate receptor by remacemide and its des-glycine metabolite. J Pharmacol Exp Ther. 1996 Jan;276(1):161-8. | |||
REF 2 | Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol. 2006 Feb;6(1):7-17. | |||
REF 3 | Neuroprotective agents for the treatment of acute ischemic stroke. Curr Neurol Neurosci Rep. 2003 Jan;3(1):9-20. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.