Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05JZQ
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| Former ID |
DNC008256
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| Drug Name |
2-(2-(pyrrolidin-1-yl)ethyl)phenol
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| Synonyms |
CHEMBL273002
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C12H17NO
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| Canonical SMILES |
C1CCN(C1)CCC2=CC=CC=C2O
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| InChI |
1S/C12H17NO/c14-12-6-2-1-5-11(12)7-10-13-8-3-4-9-13/h1-2,5-6,14H,3-4,7-10H2
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| InChIKey |
MCYUAYDQGCYEGH-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series. Bioorg Med Chem Lett. 2008 Jan 1;18(1):355-9. | |||
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