Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05KRC
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| Former ID |
DIB009815
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| Drug Name |
Emopamil
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| Synonyms |
Levemopamil
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| Drug Type |
Small molecular drug
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| Indication | Cerebrovascular ischaemia [ICD-11: 8B1Z; ICD-10: I67.8; ICD-9: 434.91] | Terminated | [1] | |
| Company |
Knoll GmbH
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| Structure |
 |
Download2D MOL |
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| Formula |
C23H30N2
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| Canonical SMILES |
CC(C)C(CCCN(C)CCC1=CC=CC=C1)(C#N)C2=CC=CC=C2
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| InChI |
1S/C23H30N2/c1-20(2)23(19-24,22-13-8-5-9-14-22)16-10-17-25(3)18-15-21-11-6-4-7-12-21/h4-9,11-14,20H,10,15-18H2,1-3H3
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| InChIKey |
DWAWDSVKAUWFHC-UHFFFAOYSA-N
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| CAS Number |
CAS 78370-13-5
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:34736
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2 receptor (5HT2R) | Target Info | Modulator | [1] |
| Calcium channel unspecific (CaC) | Target Info | Modulator | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Calcium entry and 5-HT2 receptor blockade in oliguric ischaemic acute renal failure: effects of levemopamil in conscious rats. Br J Pharmacol. 1996 Mar;117(6):1348-54. | |||
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