Drug Information
Drug General Information | Top | |||
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Drug ID |
D05LGX
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Former ID |
DNC000648
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Drug Name |
Fipamezole
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Synonyms |
Fipamezole; 150586-58-6; JP-1730; 1H-Imidazole,5-(2-ethyl-5-fluoro-2,3-dihydro-1H-inden-2-yl)-; Fipamezole [INN]; ACMC-1BZQD; AC1Q4NYS; SCHEMBL935549; AC1L4U51; SCHEMBL18826053; CHEMBL1255582; CTK4C6705; 5-(2-ethyl-5-fluoro-1,3-dihydroinden-2-yl)-1H-imidazole; KXSUAWAUCNFBQJ-UHFFFAOYSA-N; 5-(2-ethyl-5-fluoro-2,3-dihydro-1h-inden-2-yl)-1h-imidazole; BDBM50417007; SB17014; 4-(2-ethyl-5-fluoro-indan-2-yl)-1H-imidazole; L001472; 4-((2RS)-2-Ethyl-5-fluoroindan-2-yl)-1H-imidazole
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Drug Type |
Small molecular drug
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Indication | Acute myeloid leukaemia [ICD-11: 2A60] | Phase 2 | [1] | |
Structure |
Download2D MOL |
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Formula |
C14H15FN2
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Canonical SMILES |
CCC1(CC2=C(C1)C=C(C=C2)F)C3=CN=CN3
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InChI |
1S/C14H15FN2/c1-2-14(13-8-16-9-17-13)6-10-3-4-12(15)5-11(10)7-14/h3-5,8-9H,2,6-7H2,1H3,(H,16,17)
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InChIKey |
KXSUAWAUCNFBQJ-UHFFFAOYSA-N
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CAS Number |
CAS 150586-58-6
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Adrenergic receptor Alpha-2 (ADRA2) | Target Info | Antagonist | [2] |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT00559871) Safety and Efficacy Study of Fipamezole in Treatment of Motor Dysfunctions in Parkinson's Disease. U.S. National Institutes of Health. | |||
REF 2 | Emerging drugs for Parkinson's disease. Expert Opin Emerg Drugs. 2006 Sep;11(3):403-17. |
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